University Professor for 29 years at the University of Grenoble-Alpes, I have been involved in the study of human viruses and their interrelationship with the host, since the 1980s. My expertise in human virology (persistent viruses) is internationally recognized by more than 110 publications & book chapters and more than 15 patent families. The interest of my team at the Institute of Structural Biology (UGA/CEA/CNRS) goes towards transdisciplinary projects at the interface of Microbiology, Immunology, and Human and Social Sciences. Responsible for the “Health” section in the Encyclopedia of the Environment – online, we have written several chapters, in particular on the health impacts of climate change and on epigenetics. At the center of a network comprising colleagues from the Institut Pasteur in Paris, from the WHO in Geneva, we are working on the vector competence of insect cells for pathogenic viruses in humans In general, the subjects covered in my career show that all living beings (including microorganisms and man, at both ends of a scale) are interconnected and that only a global approach to research subjects can lead to the elucidation of certain questions related to the life sciences.